pybind11 provides CMake integration:

  # Easy
  set(PYBIND11_FINDPYTHON ON)
  find_package(pybind11 CONFIG REQUIRED)
  pybind11_add_module(MyModule1 src1.cpp)

  # Advanced
  find_package(Python COMPONENTS Interpreter Development)
  find_package(pybind11 CONFIG REQUIRED)
  Python_add_library(MyModule2 src2.cpp)
  target_link_libraries(MyModule2 PRIVATE pybind11::headers)